Specialization:  Synthetic Organic Chemistry. Area(s) of Research Work: Organic synthesis, Bioorganic chemistry and Medicinal Chemistry. Development of new methodologies, Asymmetric synthesis, Electroorganic synthesis.

Rese arch Activities:

    Synthesis of biologically active compounds Synthesis of New Chemical Entities (NCE’s) for biological evaluation, Custom synthesis of organic molecules.  Process development for drugs and fine chemicals (organic intermediates). Development of new reagents and reactions. Synthesis of organic molecules with novel material science applications. Application of electroorganic methods for the development of new reaction and green organic processes.

Visiting Fellowship Awards:

    JSPS postdoctoral fellowship for foreign researchers for two years (2001-2003)- Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.      

Selected Publications:

One pot assembly of Tricylco [6.2.1.01,6] undecane-4-one and related polycyclic compounds by tandem electroreductive cyclization. Masahiro Toyota, Andivelu Ilangovan, Yoshitomo Kashiwagi, Msataka Ihara Organic letters, 2004, 6(20), 3629 – 3632.

First synthesis of aza-calanolides- a new class of anti-HIV RT active compounds G.V.M. Sharma, A.Ilangovan, M,K.Gurjar, Ven.L.Narayanan, Tetrahedron, 2003, 59, 95-99.

Simple construction of bicyclo[4.3.0]nonane, bicyclo[3.3.0]octane, and related  benzo derivatives by palladium-catalysed cycloalkenylation  M. Toyota, A. Ilangovan, R. Okamoto, T. Masaki, M. Arakawa, M. Ihara Org. Lett., 2002, 4, 4293-4296.

Asymmetric Baylis Hillman reaction using sugar acrylates-synthesis of optically active a-methylene b-hydroxy alkanoates. Palakodety Radhakrishna, V.Kannan, A.Ilangovan, G.V.M.Sharma, Tetrahedron:Asymmetry  2001, 12(6), 829-837. 

Stereoselective synthesis of C-alkyl and functionalised C-alkyl glycosides using thiophene as masked C-4 synthon, Palakodety Radhakrishna, B. Lavanya, A,Ilangovan, G.V.M.Sharma, Tetrahedron Asymmetry 2000, 11(22), 4463-4472.

Alternative Lewis acids for Claisen rearrangement of allyl aryl ethers, G.V.M.Sharma, A.Ilangovan, Punnna srinivas, A.K.Mahalingam, Synlett, 2000, 615-618.

Synthesis of 5-Fluorosalicylic acid, G.V.M.Sharma, A.Ilangovan, B.Lavanya,  Synth.Commun, 2000, 30, 397- 405.

Facile acetylation of alcohols, ethers and ketals with catalytic FeCI3 in AcOH,  G.V.M. Sharma, A.K.Mahalingam, M.Nagarajan, A.Ilangovan, Pakodety Radhakrishna, Synlett, 1999, 1200-1202.

Ytterbium triflate mediated selective deprotection of acetates, G.V.M.Sharma, A.Ilangovan, Synlett, 1999, 1963-1965.

A mild and highly selective deprotective method of prenyl ethers using ytterbium  triflate,  G.V.M. Sharma, A.Ilangovan, A.K.Mahalingam,  J.Org.Chem. 1998, 63, 9103-9104.

 PATENTS

An improved process for the preparation of 2,2-dimethyl-5-[2,5-dimethylphenoxy]-pentanoic acid, known as gemfibrozil, A.V.Rama Rao, M.N.Deshmukh and A.Ilangovan,  Indian Patent:175368.

A process for the preparation of novel dipyranoquinolinones useful as anti HIV agents     M.K.Gurjar, G.V.M.Sharma, A.Ilangovan, Ven.L.Narayanan; Indian Patent : 190036.

Dipyrano-quinolinones useful as anti viral agents  and a process for preparing the same. M.K.Gurjar, G.V.M.Sharma, A.Ilangovan,Ven.L.Narayanan;  US Patent: 6,191,279