University Science Instrumentation Centre (USIC)
Bharathidasan University
Tiruchirappalli - 620 024, Tamil Nadu, India

LC-MS/MS


Working Principle

The LTQ XL extends the MSn performance of the LTQ linear ion trap with powerful new tools to generate extensive structural information for the most demanding proteomics and metabolism applications. With unparalleled sensitivity and ultra-fast cycle time, the LTQ XL delivers more information from less sample in less time. The unmatched high-quality spectra of the LTQ XL in combination with powerful new software packages deliver complete solutions for your structural elucidation questions.

The advanced XcaliburTM Data Dependent software suite, which includes the MS3 neutral loss experiment, enables rapid identification of post-translational modifications and metabolites. This feature greatly reduces the amount of time needed to analyze and interpret the data. Powerful software control and data processing in addition to innovative technology provide superior coverage for protein and metabolite analysis.

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Specific Features of the Thermo LTQ XL

  •  Electron Transfer Dissociation (ETD) enabled.
  •   Multiple dissociation techniques including PQD.
  •   Extensive coverage for predicted and unpredicted metabolites.
  •   Fast polarity switching for high sensitivity analysis of unknowns.
  •   Intelligent Data DependentTM acquisition.
  •   Platform for hybrid MSn high resolution, accurate mass.

Technical Specifications

Mass Range m/z 15 – 200
m/z 50 – 2000
Ionization MS/MS Sensitivity Electrospray Ionization (ESI)
Atmospheric Pressure Chemical Ionization (APCI)
Resolution Down to 0.05 FWHM (full width half maximum) with Ultra Zoom Scan.
Integrated Syringe Pump Syringe Pump allows automated infusion under data system control.
Transfer Ion Optics Advanced ion guides.
High stability and ion transmission efficiency.
Hardware Features Enhanced sensitivity and ruggedness.
Sweep GasTM reduces chemical noise.
60° interchangeable ion probe orientation.
Removable metal ion capillary tube provides vent-free maintenance.
2D Linear Quadrupole Ion Trap Mass Spectrometer.
Detection System.
Integrated Divert Valve.
Polarity Switching 100 milli seconds between positive and negative.
MS Scan Power MSn, for n = 1 through 15.
Software Features Xcalibur processing and instrument control software.
Vacuum System Differentially-pumped vacuum system to 10-5 Torr.
Split-flow turbomolecular pump controlling vacuum in three regions.
Dual rotary vacuum pump configuration.
High-vacuum aluminium analyser chamber.

Details of LC-MS/MS

BrandThermoFisher
ModelLTQ XL
Sponsored AgencyDST- PURSE programme (Phase I)

Tariff Details


Name of the Instrument BDU Departments Affiliated Colleges Other Universities / Institutes Industries / Non-academics
MS  750  1000  1500  2000
LCMS/MS  1000  1750  2000  2500

* Additional 18% GST.